Aires Historical Clinical Research and Original Protocols
Aires’ early development included clinical investigations of patterned applicators, with original protocols and reports preserved in the archive. These records establish the design, materials and outcomes of the historical work.
The original clinical investigations
| Investigation | Design and measured outcomes | Original |
|---|---|---|
| Adjunctive surgical care, 2000 | Thirty applicator patients and fifteen standard-care controls; pain, edema, treatment duration, thermography and coagulation observations. | Surgical protocol and report |
| Outpatient applicator study, 2000 | Thirteen active-device and six plain-film patients; six days of treatment, electropuncture readings and clinical reports. | Outpatient report |
| Fatigue/stress volunteer study, 2000 | Sixteen active and five plain-film volunteers; EEG, cognition, mood and blood/rheology measurements over repeated treatment courses. | Volunteer study |
What the reports describe
The surgical report describes faster pain and edema resolution and shorter treatment in the applicator group alongside standard clinical care. The volunteer report describes later EEG and mood improvements, with cognitive and blood findings varying by test and initial state. The original reports retain the complete results.
Which devices were tested?
These investigations concern historical patterned applicators, including graphite patterns on polyester film. Their protocol and institutional approval records belong to those studies. Device identity and study approval should be read directly from the original cover and methods.
From the early work to later physiology
The later Aires Shield EEG investigation and Aires Defender HRV report examine different devices and endpoints. The human-research guide connects them with Lifetune-era work, and the research device map distinguishes device generations.
Follow the research
Explore the Aires research program · Full research archive · Connect the research to tested devices
Updated October 25, 2026 · Josh, Aires. Original research and expert peer reviews are credited to their authors and linked above.